Comparison of interferon gamma release assay & tuberculin skin tests for diagnosis of latent tuberculosis in patients on maintenance haemodialysis
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منابع مشابه
Comparison of interferon gamma release assay & tuberculin skin tests for diagnosis of latent tuberculosis in patients on maintenance haemodialysis
BACKGROUND & OBJECTIVES Tuberculosis (TB) is a common infection in patients on haemodialysis. There is a definite role of treatment of latent TB (LTB) in these patients. However, diagnosis of LTB in these patients by tuberculin skin test (TST) is unreliable. There is suggestion that interferon gamma release assay (IGRA) will be more reliable test for diagnosis of LTB in this setting. Thus, we e...
متن کاملTuberculin Skin Testing and Treatment Modulates Interferon-Gamma Release Assay Results for Latent Tuberculosis in Migrants
BACKGROUND Identifying latent tuberculosis infection (LTBI) in people migrating from TB endemic regions to low incidence countries is an important control measure. However, no prospective longitudinal comparisons between diagnostic tests used in such migrant populations are available. OBJECTIVES To compare commercial interferon (IFN)-gamma release assays (IGRAs) and the tuberculin skin test (...
متن کاملInterferon-gamma release assays versus tuberculin skin testing for detection of latent tuberculosis in chronic haemodialysis patients.
BACKGROUND End stage renal disease increases the risk of reactivating latent tuberculosis (LTBI). Interferon-gamma release assays (IGRA) are an alternative to the tuberculin skin test (TST) for detecting LTBI. METHODS Sixty-two hemodialysis patients (46 male, 16 female, aged 65 +/- 15 years) from 3 hemodialysis facilities in the Geneva area were submitted to a TST, 2 IGRA (T-SPOT.TB and Quant...
متن کاملInterferon-gamma release assay versus tuberculin skin test for latent tuberculosis infection among HIV patients in Brazil.
SETTING Patients HIV+ attending in a reference clinic, Southern Brazil. OBJECTIVE To compare the interferon-gamma-release assay (IGRA - QuantiFERON(®) TB Gold In-Tube) with the tuberculin skin test (TST - PPD-Rt 23) for latent tuberculosis infection (LTBI) in patients with HIV. DESIGN Cohort study. Patients were simultaneously submitted to the TST and blood collection for the IGRA. RESULT...
متن کاملHigh prevalence of latent tuberculosis infection in dialysis patients using the interferon-gamma release assay and tuberculin skin test.
BACKGROUND AND OBJECTIVES Patients in ESRD on hemodialysis with latent tuberculosis (TB) infection have 10 to 25 times the risk of reactivation into active disease compared with healthy adults. This study investigates the prevalence of latent TB infection in dialysis patients from a country with an intermediate burden of TB and its associated risk factors using the QuantiFERON-TB Gold in-tube t...
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ژورنال
عنوان ژورنال: Indian Journal of Medical Research
سال: 2015
ISSN: 0971-5916
DOI: 10.4103/0971-5916.159297